Detalhe da pesquisa
1.
Synthesis and cytotoxicity studies of Hedgehog enzyme inhibitors SANT-1 and GANT-61 as anticancer agents.
J Environ Sci Health A Tox Hazard Subst Environ Eng
; 49(6): 641-7, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24521409
2.
Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations.
Carcinogenesis
; 33(11): 2242-9, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22831956
3.
Synthesis of conformationally preorganized and cell-permeable guanidine-based gamma-peptide nucleic acids (gammaGPNAs).
J Org Chem
; 74(4): 1509-16, 2009 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-19161276
4.
Combined Inhibition of Cyclin-Dependent Kinases (Dinaciclib) and AKT (MK-2206) Blocks Pancreatic Tumor Growth and Metastases in Patient-Derived Xenograft Models.
Mol Cancer Ther
; 14(7): 1532-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25931518
5.
miR-181c regulates the mitochondrial genome, bioenergetics, and propensity for heart failure in vivo.
PLoS One
; 9(5): e96820, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24810628
6.
A simple cytosine to G-clamp nucleobase substitution enables chiral gamma-PNAs to invade mixed-sequence double-helical B-form DNA.
Chembiochem
; 9(15): 2388-91, 2008 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18816545
7.
Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma.
Clin Cancer Res
; 18(5): 1291-302, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21868763
8.
A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy.
Oncotarget
; 3(6): 640-50, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22791660
9.
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists.
Mol Cancer Ther
; 11(1): 165-73, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22027695
10.
Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.
Mol Cancer Ther
; 9(8): 2255-64, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20647339